Most scientific questions are causal in nature.
It is therefore necessary to introduce a formal causal language to help define causal effects and spell out the assumptions required to infer such effects from clinical and observational data.

The potential outcome approach to causal inference will be introduced and statistical methods for inferring causal effects from randomized clinical or observational studies will be presented. Examples and practical sessions will be based on case studies in biostatistics, epidemiology, and public health.

  • Introduction to causal inference from the potential outcome perspective
  • Design and analysis of randomized clinical trials (RCT): Fisher’s exact p-values, estimators of average causal effects, regression, imputation-based approaches
    • Practical session 1: Analyzing an RCT on the effect of statins on cholesterol
  • Design and analysis of observational studies under confoundedness: the role of the propensity score; matching, weighting, regression estimators
    • Practical session 2: Analyzing an observational study on the effect of statins
  • Beyond RCTs. Intercurrent events: challenges and opportunities. Presentation of a case study with discussion

Lecture notes, slides, data, articles and other reading material will be distributed before the course.
Practical sessions will be in R but no a priori knowledge of R is required.

Main reference:
Imbens G., Rubin D.B. (2015) Causal Inference for the Statistics, Social and Biomedical Sciences: An Introduction, Cambridge University Press

Statisticians, health professionals with statistical background, master and PhD students.

Participant experience
Statistical inference, multivariate analysis are taken for granted.

Lectures with some practical sessions/examples

Fabrizia Mealli

Fabrizia Mealli

Professor of Statistics, Director of the Florence Center for Data Science at University of Florence

Fabrizia Mealli is Professor of Statistics. Her research focuses on causal inference, program evaluation, estimation techniques, simulation methods, missing data, and Bayesian inference, with applications to the social and biomedical sciences. She held visiting positions at Harvard University, UCLA, LISER Luxembourg. She serves as coordinator of the Statistics track for the PhD program in Mathematics, Computer Science, Statistics of the University of Florence, and sits the Steering Committee of the European Causal Inference Meeting. She is Elected Fellow of the American Statistical Association, and currently an associate editor of “The Annals of Applied Statistics” and “Observational Studies”.

This online training consists of 1 module:

11 October 2022 from 9:00 am to 1:00 pm CEST

Some days before the online training you will receive all details about the connection.

The course will proceed with a minimum number of participants. Should this number not be reached the registered participants will be notified one week prior to the commencement of the course.

Early Bird: € 440,00* (until 27 September 2022)

Ordinary: € 590,00*

Freelance – Academy – Public Administration**: € 265,00*

* for Italian companies: +22% VAT

** Early Bird discount not applicable to Freelance – Academy – Public Administration fee

The fee includes: tuitions, organizational office assistance, teaching materials and attendance certificate that will be sent after the training via e-mail.


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Cosa saprai fare dopo il corso
Risultato atteso
develop expertise to assess the credibility of causal claims and the ability to apply the relevant statistical methods for causal analyses

<p><span>Online interactive training on Zoom platform. </span></p>
<p><em>LS Academy will provide the access link to the virtual platform a few days before the training.</em></p>

Online interactive training on Zoom platform. 

LS Academy will provide the access link to the virtual platform a few days before the training.

<p><span>Online interactive training on Zoom platform. </span></p>
<p><em>LS Academy will provide the access link to the virtual platform a few days before the training.</em></p>