Evidence-based medicine (EBM) hierarchically organizes different sources of medical information with meta-analyses, systematic reviews, and randomised clinical trials (RCTs) which provide the strongest and most reliable evidence and patient registries which fall under observational studies classified as a source of low-level evidence.<\/p>\n
RCTs, the golden standard of medical evidence, are meant to generate unbiased data for inferring causality from observed associations whereas the observational studies are often seen as delivering poor quality information. <\/sup>However, the reality is not always so clear and straightforward. The main concern related to RCTs as guidance in medical decision-making is their applicability to daily clinical practice and generalisability to a patient population at large.<\/p>\n Real-world data (RWD) refer to any observational data collected outside of clinical trials or clinical investigations. Patient registries, belonging to the \u00a0RWD family, are gaining in importance as a source of medical information. Therefore, it is critical to understand the specificity of such data and the way they should be interpreted.<\/p>\n This course focuses on the basic concepts of real-life medical research, the differences between the data from real-life settings including patient registries and experimental trials, and their relevance in clinical context. \u00a0It will additionally provide tools for critical appraisal of the published registry data.<\/p>\n","protected":false},"excerpt":{"rendered":" Evidence-based medicine (EBM) hierarchically organizes different sources of medical information with meta-analyses, systematic reviews, and randomised clinical trials (RCTs) which provide the strongest and most reliable evidence and patient registries which fall under observational studies classified as a source of low-level evidence. RCTs, the golden standard of medical evidence, are meant to generate unbiased data … Continued<\/a><\/p>\n","protected":false},"featured_media":10390,"template":"","meta":[],"product_brand":[],"product_cat":[46],"product_tag":[],"class_list":["post-10381","product","type-product","status-publish","has-post-thumbnail","course_topics-real-world-data-e-real-world-evidence","course_topics-market-access","course_topics-medical-affairs","course_topics-ricerca-clinica","course_types-corso-online","productgroup-patient-registries","product_cat-corsi","first","instock","taxable","shipping-taxable","purchasable","product-type-variable"],"_links":{"self":[{"href":"https:\/\/lsacademy.com\/it\/wp-json\/wp\/v2\/product\/10381","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lsacademy.com\/it\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/lsacademy.com\/it\/wp-json\/wp\/v2\/types\/product"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/lsacademy.com\/it\/wp-json\/wp\/v2\/media\/10390"}],"wp:attachment":[{"href":"https:\/\/lsacademy.com\/it\/wp-json\/wp\/v2\/media?parent=10381"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/lsacademy.com\/it\/wp-json\/wp\/v2\/product_brand?post=10381"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/lsacademy.com\/it\/wp-json\/wp\/v2\/product_cat?post=10381"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/lsacademy.com\/it\/wp-json\/wp\/v2\/product_tag?post=10381"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}